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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5J
All Species:
5.15
Human Site:
S468
Identified Species:
12.59
UniProt:
Q15735
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15735
NP_001002837.1
1006
107197
S468
I
G
L
Q
E
V
N
S
M
L
N
K
R
L
K
Chimpanzee
Pan troglodytes
A0FI79
644
70203
A177
N
L
P
H
R
D
A
A
V
A
G
S
S
P
R
Rhesus Macaque
Macaca mulatta
XP_001110784
811
87406
N344
G
L
G
G
Y
W
G
N
K
G
G
V
S
V
R
Dog
Lupus familis
XP_543486
1008
107177
S470
I
G
L
Q
E
V
N
S
M
I
N
K
R
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P59644
1003
107585
K469
E
V
N
S
M
I
N
K
R
L
K
D
A
L
F
Rat
Rattus norvegicus
Q9JMC1
1001
107190
L469
N
S
M
I
N
K
R
L
K
D
A
L
F
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507443
768
84124
C301
H
M
V
C
F
L
N
C
H
L
P
A
H
M
D
Chicken
Gallus gallus
XP_415287
1011
110631
L501
S
G
F
Q
E
G
P
L
N
F
P
P
T
F
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698057
784
85922
Y317
T
R
T
G
L
G
G
Y
W
G
N
K
G
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780987
442
50512
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.8
78.9
87.5
N.A.
82.2
83.9
N.A.
56.2
42.2
N.A.
40.8
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
32.3
79.4
91.5
N.A.
86.7
88
N.A.
63.6
55.3
N.A.
51.1
N.A.
N.A.
N.A.
N.A.
29.3
P-Site Identity:
100
0
0
93.3
N.A.
20
0
N.A.
13.3
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
20
100
N.A.
26.6
6.6
N.A.
33.3
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
10
10
10
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
10
0
10
0
0
20
% D
% Glu:
10
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
10
0
0
0
0
10
0
0
10
10
10
% F
% Gly:
10
30
10
20
0
20
20
0
0
20
20
0
10
10
0
% G
% His:
10
0
0
10
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
20
0
0
10
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
10
20
0
10
30
0
0
30
% K
% Leu:
0
20
20
0
10
10
0
20
0
30
0
10
0
30
0
% L
% Met:
0
10
10
0
10
0
0
0
20
0
0
0
0
10
0
% M
% Asn:
20
0
10
0
10
0
40
10
10
0
30
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
20
10
0
10
0
% P
% Gln:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
0
10
0
10
0
0
0
20
0
20
% R
% Ser:
10
10
0
10
0
0
0
20
0
0
0
10
20
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% T
% Val:
0
10
10
0
0
20
0
0
10
0
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _